Region 23

All games are Saturday at 7 p.m.

12 KIPP Columbus (20) at 4 Barnesville (28)

Despite the loss, this was KIPP Columbus's best season in years as the Jaguars were without a winning season each of the last four years.

This 7-5, regional quarterfinals finish for KIPP Columbus suggested that the school's football program has gained a foothold in Division VI and pointed to increasing potential for the future.

6 Northmor (13) at 2 West Jefferson (63) 

West Jefferson accomplished an unprecedented 50-point win against Northmor on Saturday.

The Roughriders' win was led by three touchdowns and 70 rushing yards for running back Hayden Salyer.

Northmor suffered its worst loss of the year while allowing the most points they have all season.

After a disappointing 2020 season, Northmor's bounce back to an 8-2 regular-season record is a positive that should give the Golden Knights hope for next year.

Region 24

8 Jamestown Greenview (21) at 1 Mechanicsburg (31)

Usually impenetrable on defense, Mechanicsburg allowed its second-highest score on defense this season on its way to a 10-point win.

Rather than the relative ease with which the Indians have dominated Ohio's high school teams, Mechanicsburg had a bit of a challenge on Saturday against Jamestown Greenview.

However, the win keeps the No. 1 Indians alive and still in charge of their own destiny going into the regional semifinals.